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Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes.

NADPH oxidase is the enzyme complex responsible for the production of oxygen radicals in phagocytes. On neutrophil stimulation, the cytosolic components of NADPH oxidase, p67phox and p47phox, as well as the Ras-related G-protein rac 2, are translocated from the cytosol to cell membranes where they a...

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Библиографические подробности
Главные авторы: Dusi, S, Donini, M, Rossi, F
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136820/
https://ncbi.nlm.nih.gov/pubmed/8948460
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