Thapsigargin-sensitive Ca(2+)-ATPases account for Ca2+ uptake to inositol 1,4,5-trisphosphate-sensitive and caffeine-sensitive Ca2+ stores in adrenal chromaffin cells.

In chromaffin cells of adrenal medulla, heterogeneity of Ca2+ stores has been suggested with respect to the mechanisms of Ca2+ uptake and release. We have examined Ca(2+)-ATPases responsible for loading of Ca2+ stores in these cells for their sensitivity to thapsigargin, a highly selective inhibitor...

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Bibliographic Details
Main Authors: Poulsen, J C, Caspersen, C, Mathiasen, D, East, J M, Tunwell, R E, Lai, F A, Maeda, N, Mikoshiba, K, Treiman, M
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136714/
https://ncbi.nlm.nih.gov/pubmed/7741706
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