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Thapsigargin inhibits Ca2+ entry into human neutrophil granulocytes.

The mechanism of Ca2+ entry after ligand binding to receptors on the surface of non-excitable cells is a current focus of interest. Considerable attention has been given to Ca2+ influx induced by emptying of intracellular pools. Thapsigargin, an inhibitor of microsomal Ca(2+)-ATPase, is an important...

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Autors principals: Geiszt, M, Káldi, K, Szeberényi, J B, Ligeti, E
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136394/
https://ncbi.nlm.nih.gov/pubmed/7832770
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