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Decrease in free-radical production with age in rat peritoneal macrophages.

The respiratory-burst reaction has been studied in rat peritoneal macrophages of different ages (3, 12 and 24 months) using phorbol 12-myristate 13-acetate (PMA) to stimulate NADPH oxidase. Production of O2-. and H2O2 decreased with age (about 50 and 75% respectively); however, no difference in NADP...

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Detalhes bibliográficos
Main Authors: Alvarez, E, Conde, M, Machado, A, Sobrino, F, Santa Maria, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136298/
https://ncbi.nlm.nih.gov/pubmed/8526870
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