Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors.

In isolated rat hepatocytes, a radiolabelled tyramine-cellobiose conjugate of asialo-orosomucoid, 125I-TC-AOM, was rapidly taken up by receptor-mediated endocytosis and proteolytically degraded in the lysosomes, where radioactive degradation products accumulated. Okadaic acid and other protein phosp...

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Bibliografski detalji
Glavni autori: Holen, I, Gordon, P B, Strømhaug, P E, Berg, T O, Fengsrud, M, Brech, A, Roos, N, Berg, T, Seglen, P O
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136154/
https://ncbi.nlm.nih.gov/pubmed/7575471
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