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Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I.

The regulation of hepatic mitochondrial carnitine palmitoyltransferase-I (CPT-I) was studied in rats during starvation and insulin-dependent diabetes and in rat H4IIE cells. The Vmax. for CPT-I in hepatic mitochondrial outer membranes isolated from starved and diabetic rats increased 2- and 3-fold r...

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Détails bibliographiques
Auteurs principaux: Park, E A, Mynatt, R L, Cook, G A, Kashfi, K
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135974/
https://ncbi.nlm.nih.gov/pubmed/7575418
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