Structural and functional analysis of the canine histamine H2 receptor by site-directed mutagenesis: N-glycosylation is not vital for its action.

G-protein-coupled receptors generally share a similar structure containing seven membrane-spanning domains and extracellular site(s) for N-glycosylation. The histamine H2 receptor is a member of the family of G-protein-coupled receptors, and has three extracellular potential sites for N-glycosylatio...

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Detalhes bibliográficos
Main Authors: Fukushima, Y, Oka, Y, Saitoh, T, Katagiri, H, Asano, T, Matsuhashi, N, Takata, K, van Breda, E, Yazaki, Y, Sugano, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135930/
https://ncbi.nlm.nih.gov/pubmed/7544576
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