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Glutamate stably enhances the activity of two cytosolic forms of phospholipase A2 in brain cortical cultures.

The mechanisms by which glutamatergic neurotransmitters modulate neuronal lipid metabolism are not well established. We have directly measured phospholipase A2 (PLA2) enzymic activity in cell-free extracts from cortical neuronal cultures from rat brain and have found that the PLA2 activity is up-reg...

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Autors principals: Kim, D K, Rordorf, G, Nemenoff, R A, Koroshetz, W J, Bonventre, J V
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135857/
https://ncbi.nlm.nih.gov/pubmed/7646475
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