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Anion dependence of bumetanide binding and ion transport by the rabbit parotid Na(+)-K(+)-2Cl- co-transporter: evidence for an intracellular anion modifier site.

The anion dependence of [3H]bumetanide binding and 22Na+ transport by the rabbit parotid Na(+)-K(+)-2Cl- co-transporter was studied in acinar basolateral membrane vesicles (BLMVs). Cl-, Br- and NO3- have a biphasic effect on binding consistent with the presence of two anion sites associated with the...

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Detalhes bibliográficos
Main Authors: Moore, M L, George, J N, Turner, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135778/
https://ncbi.nlm.nih.gov/pubmed/7626030
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