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Guanine nucleotides induce tyrosine phosphorylation and activation of the respiratory burst in neutrophils.

Activation of the NADPH oxidase was examined in electrically permeabilized human neutrophils exposed to non-hydrolysable guanine nucleotides. Guanosine 5'-[gamma-thio]triphosphate (GTP[S]) induced a marked increase in the rate of O2 consumption, which was partially resistant to staurosporine, a...

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Dettagli Bibliografici
Autori principali: Nasmith, P E, Mills, G B, Grinstein, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135671/
https://ncbi.nlm.nih.gov/pubmed/2930492
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