Caricamento...

Interference of blood-coagulation vitamin K-dependent proteins in the activation of human protein C. Involvement of the 4-carboxyglutamic acid domain in two distinct interactions with the thrombin-thrombomodulin complex and with phospholipids.

Human protein C is the precursor of a serine proteinase in plasma which contains nine 4-carboxyglutamic acid residues and functions as a potent anticoagulant. It is activated by thrombin in the presence of an essential endothelial-cell-membrane glycoprotein cofactor, thrombomodulin. In a purified hu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Freyssinet, J M, Beretz, A, Klein-Soyer, C, Gauchy, J, Schuhler, S, Cazenave, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135438/
https://ncbi.nlm.nih.gov/pubmed/2851994
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !