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Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

The capacity of cyclosporin A to inhibit opening of a Ca2+-dependent pore in the inner membrane of heart mitochondria was investigated. Whereas in the presence of 25 nmol of Ca2+/mg of mitochondrial protein and 5 mM-Pi mitochondria were unable to maintain accumulated Ca2+, inner-membrane potential a...

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Hlavní autoři: Crompton, M, Ellinger, H, Costi, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135230/
https://ncbi.nlm.nih.gov/pubmed/3196322
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