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Design and biological activity of a new generation of synthetic C3a analogues by combination of peptidic and non-peptidic elements.

Based on published X-ray crystallographic data of the anaphylatoxic complement peptide C3a, we have synthesized a series of peptides with appropriate amino acid exchanges and a maximal length of 13 amino acids. N-terminal acylation of these optimized structures with epsilon-aminohexanoic acid and co...

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Detalhes bibliográficos
Main Authors: Gerardy-Schahn, R, Ambrosius, D, Casaretto, M, Grötzinger, J, Saunders, D, Wollmer, A, Brandenburg, D, Bitter-Suermann, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135211/
https://ncbi.nlm.nih.gov/pubmed/3264156
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