Mice Are Protected from Helicobacter pylori Infection by Nasal Immunization with Attenuated Salmonella typhimurium phoP(c) Expressing Urease A and B Subunits

Live Salmonella typhimurium phoP(c) bacteria were tested as mucosal vaccine vectors to deliver Helicobacter pylori antigens. The genes encoding the A and B subunits of H. pylori urease were introduced into S. typhimurium phoP(c) and expressed under the control of a constitutive tac promoter (tac-ure...

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Main Authors: Corthésy-Theulaz, Irène E., Hopkins, Sally, Bachmann, Daniel, Saldinger, Pierre F., Porta, Nadine, Haas, Rainer, Zheng-Xin, Yan, Meyer, Thomas, Bouzourène, Hanifa, Blum, André L., Kraehenbuhl, Jean-Pierre
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC113500/
https://ncbi.nlm.nih.gov/pubmed/9453612
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