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Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5′-UTR splice variants with altered translational activities

In humans, a polymorphic gene encodes the drug-metabolizing enzyme NAT1 (arylamine N-acetyltransferase Type 1), which is widely expressed throughout the body. While the protein-coding region of NAT1 is contained within a single exon, examination of the human EST (expressed sequence tag) database at...

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Detalhes bibliográficos
Main Authors: Butcher, Neville J., Arulpragasam, Ajanthy, Goh, Hui Li, Davey, Tamara, Minchin, Rodney F.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134939/
https://ncbi.nlm.nih.gov/pubmed/15487985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040903
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