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9-cis-retinoic acid is a natural antagonist for the retinoic acid receptor response pathway.

The pleiotropic activities of retinoids are mediated by two types of nuclear receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). All-trans-retinoic acid (RA) transcriptionally activates RARs, but not RXRs, whereas its natural stereoisomer, 9-cis-RA, is the ligand for R...

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Main Authors: Carlberg, C, Saurat, J H, Siegenthaler, G
格式: Artigo
語言:Inglês
出版: 1993
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134887/
https://ncbi.nlm.nih.gov/pubmed/8240231
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