The helix-loop-helix transcription factor USF (upstream stimulating factor) binds to a regulatory sequence of the human insulin gene enhancer.

Two important sequence elements, designated insulin enhancer binding site 1 (IEB1) or NIR and IEB2 or FAR, are involved in regulating expression of the rat insulin I gene. These elements bind a helix-loop-helix transcription factor, insulin enhancer factor 1 (IEF1). The IEB1 site is highly conserved...

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Main Authors: Read, M L, Clark, A R, Docherty, K
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134844/
https://ncbi.nlm.nih.gov/pubmed/8216223
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