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Identification of the predominant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosyltransferase competition for serine474.

Thrombomodulin (TM) is an endothelial cell thrombin receptor that converts thrombin from a procoagulant to an anticoagulant enzyme. It has previously been shown that TM is expressed in both a high-M(r) form containing chondroitin sulphate and a low-M(r) form lacking this modification. Site-directed...

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Main Authors: Gerlitz, B, Hassell, T, Vlahos, C J, Parkinson, J F, Bang, N U, Grinnell, B W
格式: Artigo
語言:Inglês
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134829/
https://ncbi.nlm.nih.gov/pubmed/8216207
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