Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins

Autophagic activity in isolated rat hepatocytes is strongly suppressed by OA (okadaic acid) and other PP (protein phosphatase)-inhibitory toxins as well as by AICAR (5-aminoimidazole-4-carboxamide riboside), a direct activator of AMPK (AMP-activated protein kinase). To investigate whether AMPK is a...

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Detalhes bibliográficos
Main Authors: Samari, Hamid R., Møller, Michael T. N., Holden, Lise, Asmyhr, Tonje, Seglen, Per O.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134787/
https://ncbi.nlm.nih.gov/pubmed/15461583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040609
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