The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo

In Drosophila cells, phosphorylation of eIF4E (eukaryotic initiation factor 4E) is required for growth and development. In Drosophila melanogaster, LK6 is the closest homologue of mammalian Mnk1 and Mnk2 [MAPK (mitogen-activated protein kinase) signal-integrating kinases 1 and 2 respectively] that p...

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Autores principales: Parra-Palau, Josep L., Scheper, Gert C., Harper, Daniel E., Proud, Christopher G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2005
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134744/
https://ncbi.nlm.nih.gov/pubmed/15487973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040769
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