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Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-β-induced apoptosis in ovarian carcinoma

Previously, we have reported that overexpression of IHPK2 (inositol hexakisphosphate kinase 2) sensitized NIH-OVCAR-3 ovarian carcinoma cell lines to the growth-suppressive and apoptotic effects of IFN-β (interferon-β) treatment and γ-irradiation. In the present study, we demonstrate that Apo2L/TRAI...

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Autores principales: Morrison, Bei H., Tang, Zhuo, Jacobs, Barbara S., Bauer, Joseph A., Lindner, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134734/
https://ncbi.nlm.nih.gov/pubmed/15634191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040971
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