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Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization
Proteinase 3C of hepatitis A virus (HAV) plays a key role in the viral life cycle by generating mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, 3C binds to viral RNA, and thus influences viral genome replication. In order to investigate the interplay be...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134706/ https://ncbi.nlm.nih.gov/pubmed/15361063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041153 |
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