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Human cyclo-oxygenase-1 and an alternative splice variant: contrasts in expression of mRNA, protein and catalytic activities

The two COX (cyclo-oxygenase) isoenzymes COX-1 and -2 catalyse the initial step in the conversion of arachidonic acid into PG (prostaglandin) hormones. The identification of an mRNA transcript encoding a splice variant of human COX-1 was reported more than a decade ago [Diaz, Reginato and Jimenez (1...

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Detalhes bibliográficos
Main Authors: Schneider, Claus, Boeglin, William E., Brash, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134673/
https://ncbi.nlm.nih.gov/pubmed/15361066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041115
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