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Arginine mutations within a transmembrane domain of Tar, an Escherichia coli aspartate receptor, can drive homodimer dissociation and heterodimer association in vivo

The interactions between the TM (transmembrane) domains of many membrane proteins are important for their proper functioning. Mutations of residues into positively charged ones within TM domains were reported to be involved in many genetic diseases, possibly because these mutations affect the self-...

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Bibliografske podrobnosti
Main Authors: Sal-Man, Neta, Shai, Yechiel
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134670/
https://ncbi.nlm.nih.gov/pubmed/15330757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041022
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