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Arginine mutations within a transmembrane domain of Tar, an Escherichia coli aspartate receptor, can drive homodimer dissociation and heterodimer association in vivo

The interactions between the TM (transmembrane) domains of many membrane proteins are important for their proper functioning. Mutations of residues into positively charged ones within TM domains were reported to be involved in many genetic diseases, possibly because these mutations affect the self-...

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Detalhes bibliográficos
Main Authors: Sal-Man, Neta, Shai, Yechiel
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134670/
https://ncbi.nlm.nih.gov/pubmed/15330757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041022
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