Retinoic acid regulates ornithine decarboxylase gene expression at the transcriptional level.

Retinoic acid (RA) is important for normal mammalian development and growth. Ornithine decarboxylase (ODC) is the first and rate-limiting enzyme in the biosynthesis of the polyamines, and we have previously shown that ODC mRNA levels are suppressed by RA in human skin cells. Using HeLa cells, we now...

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Bibliographic Details
Main Authors: Mao, Y, Gurr, J A, Hickok, N J
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134606/
https://ncbi.nlm.nih.gov/pubmed/8240270
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