Thrombin and thrombin receptor agonist peptide induce tyrosine phosphorylation and tyrosine kinases in the platelet cytoskeleton. Translocation of pp60c-src and integrin alpha IIb beta 3 (glycoprotein IIb/IIIa) is not required for aggregation, but is dependent on formation of large aggregate structures.

類似資料

• Glycoprotein IIb-IIIa and the translocation of Rap2B to the platelet cytoskeleton.
  著者:: Torti, M, 等
  出版事項: (1994)
• Regulation of platelet glycoprotein IIb/IIIa (integrin alpha IIB beta 3) function via the thrombin receptor.
  著者:: Giesberts, A N, 等
  出版事項: (1995)
• Translocation of pp60c-src to the cytoskeleton during platelet aggregation.
  著者:: Horvath, A R, 等
  出版事項: (1992)
• Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets.
  著者:: Ferrell, J E, 等
  出版事項: (1989)
• Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins
  出版事項: (1990)