Interleukin-1 beta regulation of fibroblast proteoglycan synthesis involves a decrease in versican steady-state mRNA levels.

This study investigates the effects of interleukin (IL)-1 beta on proteoglycan metabolism by fibroblasts surrounded by endogenous extracellular matrix. In both three-dimensional matrix cultures and long-term monolayer cultures IL-1 beta caused a significant decrease in synthesis and deposition of su...

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Bibliografske podrobnosti
Main Authors: Qwarnström, E E, Järveläinen, H T, Kinsella, M G, Ostberg, C O, Sandell, L J, Page, R C, Wight, T N
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134499/
https://ncbi.nlm.nih.gov/pubmed/8373377
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