Effect of betaine on HSP70 expression and cell survival during adaptation to osmotic stress.

Induced expression of the HSP70 gene in 3T3 and SV-3T3 cells was monitored by measurements of the synthesis of HSP70 and of the cellular contents of both HSP70 and its mRNA. The presence of betaine (N-trimethylglycine) at concentrations of 2.5-25 mM decreased the induction of HSP70 gene expression c...

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Main Authors: Petronini, P G, De Angelis, E M, Borghetti, A F, Wheeler, K P
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134397/
https://ncbi.nlm.nih.gov/pubmed/8343134
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