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Digestion of damaged DNA by the T7 DNA polymerase-exonuclease.

We have investigated the 3'-5'-exonuclease activity of phage T7 DNA polymerase for its usefulness as an approach for the detection of lesions in DNA. Unlike the T4 DNA polymerase-exonuclease, which is commonly used to map the position and frequency of lesions in very small DNA fragments, T...

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Détails bibliographiques
Auteurs principaux: Koehler, D R, Hanawalt, P C
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134381/
https://ncbi.nlm.nih.gov/pubmed/8343124
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