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Structural requirements for the interaction between tissue factor and factor VII: characterization of chymotrypsin-derived tissue factor polypeptides.

Tissue Factor (TF) is the cellular receptor for coagulation Factor VII/VIIa (FVII/VIIa). TF binds to FVIIa and promotes the rapid activation of the zymogen substrates Factors IX and X (FIX and FX) to the respective serine proteinases. In order to probe structure-function relationships in TF, we have...

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Détails bibliographiques
Auteurs principaux: O'Brien, D P, Anderson, J S, Martin, D M, Byfield, P G, Tuddenham, E G
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134260/
https://ncbi.nlm.nih.gov/pubmed/8503864
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