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Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes

Caveolae, the specialized invaginations of plasma membranes, formed sealed vesicles with outwards-orientated cytosolic surface after isolation from primary human adipocytes. This morphology allowed differential, vectorial identification of proteins at the opposite membrane surfaces by proteolysis an...

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Hlavní autoři: Aboulaich, Nabila, Vainonen, Julia P., Strålfors, Peter, Vener, Alexander V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134064/
https://ncbi.nlm.nih.gov/pubmed/15242332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040647
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