Heparan sulphate proteoglycans interact with neurocan and promote neurite outgrowth from cerebellar granule cells

We found that neurocan, a major brain chondroitin sulphate proteoglycan, interacts with HSPGs (heparan sulphate proteoglycans) such as syndecan-3 and glypican-1. Binding of these HSPGs to neurocan was prevented by treatment of the HSPGs with heparitinases I and II, but not by treatment of neurocan w...

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Detalhes bibliográficos
Main Authors: Akita, Kaoru, Toda, Munetoyo, Hosoki, Yuki, Inoue, Mizue, Fushiki, Shinji, Oohira, Atsuhiko, Okayama, Minoru, Yamashina, Ikuo, Nakada, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134051/
https://ncbi.nlm.nih.gov/pubmed/15198637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040585
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