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Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism

In the RAS (renin–angiotensin system), Ang I (angiotensin I) is cleaved by ACE (angiotensin-converting enzyme) to form Ang II (angiotensin II), which has effects on blood pressure, fluid and electrolyte homoeostasis. We have examined the kinetics of angiotensin peptide cleavage by full-length human...

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Bibliografiske detaljer
Main Authors: Rice, Gillian I., Thomas, Daniel A., Grant, Peter J., Turner, Anthony J., Hooper, Nigel M.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134042/
https://ncbi.nlm.nih.gov/pubmed/15283675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040634
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