Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47–57) and penetratin(43–58)

We assessed the metabolic degradation kinetics and cleavage patterns of some selected CPP (cell-penetrating peptides) after incubation with confluent epithelial models. Synthesis of N-terminal CF [5(6)-carboxyfluorescein]-labelled CPP, namely hCT (human calcitonin)-derived sequences, Tat(47–57) and...

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Detalhes bibliográficos
Main Authors: TRéHIN, Rachel, Nielsen, Hanne M., Jahnke, Heinz-Georg, Krauss, Ulrike, Beck-Sickinger, Annette G., Merkle, Hans P.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133970/
https://ncbi.nlm.nih.gov/pubmed/15193145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040238
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