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The nuclear bile acid receptor FXR is activated by PGC-1α in a ligand-dependent manner

The nuclear bile acid receptor FXR (farnesoid X receptor) is one of the key factors that suppress bile acid biosynthesis in the liver. PGC-1α [PPARγ (peroxisome-proliferator-activated receptor γ) co-activator-1α] is known to control energy homoeostasis in adipose tissue, skeletal muscle and liver. W...

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Detalhes bibliográficos
Main Authors: Kanaya, Eiko, Shiraki, Takuma, Jingami, Hisato
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133967/
https://ncbi.nlm.nih.gov/pubmed/15202934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040432
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