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The nuclear bile acid receptor FXR is activated by PGC-1α in a ligand-dependent manner
The nuclear bile acid receptor FXR (farnesoid X receptor) is one of the key factors that suppress bile acid biosynthesis in the liver. PGC-1α [PPARγ (peroxisome-proliferator-activated receptor γ) co-activator-1α] is known to control energy homoeostasis in adipose tissue, skeletal muscle and liver. W...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133967/ https://ncbi.nlm.nih.gov/pubmed/15202934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040432 |
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