Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1)

Solute carrier family 11 member 1 (Slc11a1, formerly Nramp1) is a highly glycosylated, 12 transmembrane domain protein expressed in macrophages. It resides in the membrane of late endosomes and lysosomes, where it functions as a bivalent cation transporter. Mice susceptible to infection by various i...

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Bibliographische Detailangaben
Hauptverfasser: White, Jacqueline K., Stewart, Abigail, Popoff, Jean-Francois, Wilson, Shona, Blackwell, Jenefer M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2004
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133956/
https://ncbi.nlm.nih.gov/pubmed/15202932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040808
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