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Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells

In hypertonic environment, taurine accumulates in cells via activation of TauT (taurine transporter) as an adaptive regulation. Recent studies revealed that TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway regulated the expression of various molecules which protect cells agai...

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Detalhes bibliográficos
Main Authors: Ito, Takashi, Fujio, Yasushi, Hirata, Mayo, Takatani, Tomoka, Matsuda, Takahisa, Muraoka, Satoko, Takahashi, Kyoko, Azuma, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133928/
https://ncbi.nlm.nih.gov/pubmed/15142033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031838
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