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Binding of α(2)-macroglobulin to GRAB (Protein G-related α(2)-macroglobulin-binding protein), an important virulence factor of group A streptococci, is mediated by two charged motifs in the ΔA region
GRAB (Protein G-related α(2)M-binding protein) is a surface protein of group A streptococci and exhibits high affinity for α(2)-macroglobulin (α(2)M), a broad-range protease inhibitor. It is the sole α(2)M-binding protein of group A streptococci that has been shown to promote bacterial virulence in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133899/ https://ncbi.nlm.nih.gov/pubmed/15113281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030919 |
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