Transcriptional repression of the CTP:phosphocholine cytidylyltransferase gene by sphingosine

We examined the effects of the bioactive lipid, sphingosine, on the expression of the rate-limiting enzyme involved in surfactant phosphatidylcholine synthesis, CCTα (CTP:phosphocholine cytidylyltransferase α). Sphingosine decreased phosphatidylcholine synthesis by inhibiting CCT activity in primary...

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Detalhes bibliográficos
Main Authors: Ryan, Alan J., Fisher, Kurt, Thomas, Christie P., Mallampalli, Rama K.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133833/
https://ncbi.nlm.nih.gov/pubmed/15139854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040105
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