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Cloning, expression in Escherichia coli and characterization of the recombinant Neu5Acα2,6Galβ1,4GlcNAc-specific high-affinity lectin and its mutants from the mushroom Polyporus squamosus
Lectin from the mushroom Polyporus squamosus (PSL) has a unique carbohydrate-binding specificity for sialylated glycoconjugates containing Neu5Acα2,6Galβ1,4Glc/GlcNAc trisaccharide sequences of asparagine-linked glycoproteins. In the present study, we elucidate the molecular basis for its binding sp...
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Hoofdauteurs: | , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Portland Press Ltd.
2004
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133824/ https://ncbi.nlm.nih.gov/pubmed/15176950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040391 |
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