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Biosynthesis of UDP-GlcA, a key metabolite for capsular polysaccharide synthesis in the pathogenic fungus Cryptococcus neoformans

UDP-glucose dehydrogenase catalyses the conversion of UDP-glucose into UDP-GlcA, a critical precursor for glycan synthesis across evolution. We have cloned the gene encoding this important enzyme from the opportunistic pathogen Cryptococcus neoformans. In this fungus, UDP-GlcA is required for the sy...

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Bibliografski detalji
Glavni autori: Bar-Peled, Maor, Griffith, Cara L., Ory, Jeramia J., Doering, Tamara L.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133770/
https://ncbi.nlm.nih.gov/pubmed/15030319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031075
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