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Transcriptional control of the alpha 1(I) collagen gene involves orientation- and position-specific intronic sequences.

The 3' half of the first intron of the human alpha 1(I) collagen gene interacts with the promoter to regulate transcription. We questioned whether this intronic sequence also exerted its effect when placed 5' to the promoter. In transient transfection assays using several cell lines, littl...

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Bibliographic Details
Main Authors: Sherwood, A L, Bornstein, P
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133716/
https://ncbi.nlm.nih.gov/pubmed/2306222
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