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The selectivity of statine-based inhibitors against various human aspartic proteinases.

The interactions of five human enzymes (renin, pepsin, gastricsin, cathepsin D and cathepsin E) and the aspartic proteinase from Endothia parasitica with several series of synthetic inhibitors were examined. All of the inhibitors contained the dipeptide analogue statine or its phenylalanine or cyclo...

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Detalhes bibliográficos
Main Authors: Jupp, R A, Dunn, B M, Jacobs, J W, Vlasuk, G, Arcuri, K E, Veber, D F, Perlow, D S, Payne, L S, Boger, J, de Laszlo, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133712/
https://ncbi.nlm.nih.gov/pubmed/2407237
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