Promethazine inhibits the formation of aldehydic products of lipid peroxidation but not covalent binding resulting from the exposure of rat liver fractions to CCl4.

Promethazine is known to have protective activity in relation to CCl4-induced liver necrosis. This hepatoprotective property has been investigated with regard to the free radical scavenging and antioxidant properties of promethazine using isolated hepatocytes and microsomal suspensions. CCl4 is acti...

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Detalhes bibliográficos
Main Authors: Poli, G, Cheeseman, K H, Biasi, F, Chiarpotto, E, Dianzani, M U, Esterbauer, H, Slater, T F
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133611/
https://ncbi.nlm.nih.gov/pubmed/2604730
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