Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells.

Effects of protein kinase C (PKC) activation on the insulin-secretory process were investigated, by using beta-cell-rich suspensions obtained from pancreatic islets of obese-hyperglycaemic mice. The phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA), which is known to activate PKC directly, th...

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Главные авторы: Arkhammar, P, Nilsson, T, Welsh, M, Welsh, N, Berggren, P O
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133565/
https://ncbi.nlm.nih.gov/pubmed/2690820
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