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Inhibition of the purified human red-cell Ca2+ pump by a monoclonal antibody.

1. A monoclonal antibody (1G4) was raised against the red-cell Ca2+ pump, and it reacted with the pump, as verified by Western blot analysis and by the e.l.i.s.a. method. 2. At 1 mM-ATP and 10 microM-Ca2+, 1G4 inhibited the activity of the purified Ca2+ pump by 40%. 3. Ca2+ pump inhibition by the an...

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Autores principales: Caride, A J, Enyedi, A, Penniston, J T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133550/
https://ncbi.nlm.nih.gov/pubmed/2532506
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