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Mitogen-induced phosphorylation of human B-lymphocyte proteins. Relationship to protein kinase C activation.

We have investigated the rapid phosphorylation of proteins in B-lymphocytes incubated with the tumour-promoting phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA), anti-Ig and combinations of TPA and the Ca2+ ionophore ionomycin. Two-dimensional electrophoretic analysis was used to identify th...

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Detalhes bibliográficos
Main Authors: Guy, G R, Finney, M, Michell, R H, Gordon, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133390/
https://ncbi.nlm.nih.gov/pubmed/2604706
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