Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction.

Treatment of pancreatic islets with interleukin 1 (IL-1) results in a time-dependent inhibition of glucose-stimulated insulin secretion which has recently been demonstrated to be dependent on the metabolism of L-arginine to nitric oxide. In this report IL-1 beta is shown to induce the accumulation o...

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Detalhes bibliográficos
Main Authors: Corbett, J A, Wang, J L, Hughes, J H, Wolf, B A, Sweetland, M A, Lancaster, J R, McDaniel, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133148/
https://ncbi.nlm.nih.gov/pubmed/1384465
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