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Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites.

In order to investigate the binding mode of E64-c (a synthetic cysteine proteinase inhibitor) to papain at the atomic level, the crystal structure of the complex was analysed by X-ray diffraction at 1.9 A (1 A is expressed in SI units as 0.1 nm) resolution. The crystal has a space group P2(1)2(1)2(1...

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Autores principales: Kim, M J, Yamamoto, D, Matsumoto, K, Inoue, M, Ishida, T, Mizuno, H, Sumiya, S, Kitamura, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133078/
https://ncbi.nlm.nih.gov/pubmed/1445241
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