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Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation.

Tissue-type plasminogen activator (t-PA) is synthesized in mammalian cells as a mixture of two forms that differ in their extent of N-linked glycosylation. We have investigated the mechanism underlying this variation in glycosylation, using a cell-free system that consists of a rabbit reticulocyte l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bulleid, N J, Bassel-Duby, R S, Freedman, R B, Sambrook, J F, Gething, M J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133051/
https://ncbi.nlm.nih.gov/pubmed/1520279
Etiketak: Etiketa erantsi
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